Neurostimulation Techniques: TMS, DBS, and Emerging Brain Modulation Therapies

Neurostimulation therapies are redefining treatment options for individuals with refractory psychiatric conditions. Transcranial Magnetic Stimulation (TMS) and Deep Brain Stimulation (DBS) have demonstrated significant benefits in treatment-resistant depression, obsessive-compulsive disorder, and certain mood disorders. Emerging brain modulation techniques, including transcranial direct current stimulation (tDCS) and focused ultrasound, are expanding non-invasive and precision-based therapeutic possibilities. Advances in neuro-navigation, imaging guidance, and individualized targeting are improving safety, tolerability, and response rates. These technologies modulate neural circuits associated with mood regulation, cognition, and emotional processing, offering alternatives when pharmacotherapy is insufficient. Ongoing research focuses on optimizing stimulation parameters, identifying predictive biomarkers of response, and integrating neurostimulation with psychotherapy and medication management. As clinical evidence grows, brain modulation therapies are becoming increasingly integrated into hospital-based psychiatric services worldwide.

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