Precision Psychiatry: Biomarkers, Genetics, and Personalized Treatment

Precision psychiatry is advancing beyond symptom-based diagnosis toward biologically informed treatment strategies. Genetic profiling, inflammatory markers, neurochemical signatures, and pharmacogenomic testing are helping clinicians predict medication response and adverse effects. Research into gene-environment interactions and epigenetic mechanisms is deepening understanding of complex psychiatric disorders. Personalized treatment planning reduces trial-and-error prescribing and improves therapeutic effectiveness, particularly in mood and psychotic disorders. Integration of multi-omics data with clinical assessment tools enables stratified care models tailored to individual risk profiles. While challenges remain in standardization and accessibility, precision approaches promise to improve treatment response rates, reduce chronicity, and support long-term recovery through targeted, patient-centered interventions.

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